Updated
Immune function
Shiitake, cordyceps, reishi and four others have been tried in people for this. The register's own words for this are immune function, immunity, infection, common cold, vaccine response.
Thirteen registered trials have looked at this, and not one of them has reported a result.
Species by species
| Species | How far it has got | Trials | With a result | Randomised | Commonly taken for it |
|---|---|---|---|---|---|
| Mesima Phellinus linteus | Repeated trials | 0 | 0 | 2 | yes |
| Oyster mushroom Pleurotus ostreatus | Repeated trials | 0 | 0 | 5 | yes |
| Shiitake Lentinula edodes | A first trial | 3 | 0 | 1 | yes |
| Cordyceps Cordyceps militaris | A first trial | 2 | 0 | 1 | — |
| Reishi Ganoderma lucidum | A first trial | 2 | 0 | 1 | yes |
| Turkey tail Trametes versicolor | Being tested now | 2 | 0 | 0 | yes |
| Cauliflower fungus Sparassis crispa | Being tested now | 1 | 0 | 0 | yes |
| Poria Wolfiporia extensa | Being tested now | 1 | 0 | 0 | — |
| Zhu ling Polyporus umbellatus | Being tested now | 1 | 0 | 0 | — |
| Agarikon Fomitopsis officinalis | Laboratory work | 0 | 0 | 0 | yes |
| Artist's conk Ganoderma applanatum | Laboratory work | 0 | 0 | 0 | yes |
| Button mushroom Agaricus bisporus | Laboratory work | 0 | 0 | 0 | yes |
| Chaga Inonotus obliquus | Laboratory work | 0 | 0 | 0 | yes |
| Chicken of the woods Laetiporus sulphureus | Laboratory work | 0 | 0 | 0 | yes |
| Enoki Flammulina velutipes | Laboratory work | 0 | 0 | 0 | yes |
| King oyster Pleurotus eryngii | Laboratory work | 0 | 0 | 0 | yes |
| Maitake Grifola frondosa | Laboratory work | 0 | 0 | 0 | yes |
| Morel Morchella esculenta | Laboratory work | 0 | 0 | 0 | yes |
| Royal sun agaric Agaricus subrufescens | Laboratory work | 0 | 0 | 0 | yes |
| Shimeji Hypsizygus marmoreus | Laboratory work | 0 | 0 | 0 | yes |
| Tremella Tremella fuciformis | Laboratory work | 0 | 0 | 0 | yes |
Commonly taken for immune function, with the work still in the laboratory rather than in people: Mesima, Oyster mushroom, Agarikon, Artist's conk, Button mushroom, Chaga, Chicken of the woods, Enoki, King oyster, Maitake, Morel, Royal sun agaric, Shimeji, Tremella.
The trials themselves
Every registered study that names one of these species and a condition the register files under this heading.
| Register | Study | Condition | People | Status | Result posted | Dose in the protocol |
|---|---|---|---|---|---|---|
| NCT04846010 | Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2 | Sequelae of; Infection, Post Infection Glomerulonephritis | 2000 | Unknown | — | — |
| NCT04846010 | Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2 | Sequelae of; Infection, Post Infection Glomerulonephritis | 2000 | Unknown | — | — |
| NCT06752083 | Efficacy of Lentinula Edodes-Derived Supplement (AHCC®) in Promoting Negativity of Persistent HPV Infection | HPV Infection | 289 | Completed | — | — |
| NCT04210336 | Clinical Trial to Evaluate Papilocare® Gel Efficacy Into Repairment of Cervical Lesions Caused by HPV | HPV Infection, Lesion Cervix | 200 | Completed | — | — |
| NCT04914143 | the Effect of Broken Ganoderma Lucidum Spore Powder on Quality of Life and Immune Function in Patients With Di | Diffuse Large B-cell Lymphoma | 120 | Unknown | — | — |
| NCT05508529 | Natural Modulators of Immune Function and Mood one ingredient in a multi-herb preparation | Stress | 120 | Completed | — | — |
| NCT02244372 | Efficacy and Safety of Cordyceps Sinensis Mycelium Culture Extract(Paecilomyces Hepiali, CBG-CS-2) on Promotio | Immunity | 90 | Completed | — | 0.76 g, 1.15 g |
| NCT04624568 | Papilocare®: Effects on Regression of Histologically Confirmed Cervical Intraepithelial Lesions 1 and Toleranc | Squamous Intraepithelial Lesions of the Cervix, Human Papill | 81 | Completed | — | — |
| NCT02814617 | The Efficacy and Safety of Cordyceps Sinensis Mycelium Culture Extract(Paecilomyces Hepiali, CBG-CS-2) on Prom | Immunity | 80 | Completed | — | 1.68 g |
| NCT04633330 | Evaluation of AHCC® for the Clearance of High Risk-HPV Infections in Chinese Female | High Risk Human Papillomavirus Infection, Low Grade Squamous | 60 | Unknown | — | — |
| NCT07479394 | Impact of AHCC® Supplementation for Prevention of Respiratory Tract Infections Among Children Age 4-6 Years Ol | Respiratory Tract Infections (RTI) | 60 | Not yet recruiting | — | — |
| NCT01736787 | Efficacy and Safety of Cauliflower Mushroom Extract on Promotion of Immunity | Immunity | 60 | Completed | — | 1g/day |
| NCT03589781 | Investigating the Effects of Mikei® Red Reishi Essence EX on the Immune System of Prostate Cancer Patients and | Prostate Cancer | — | Withdrawn | — | 490 mg, 3 capsule |
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