Updated
Memory and focus
Lion's mane, reishi, cordyceps and tremella have been tried in people for this. The register's own words for this are cognition, cognitive function, memory, mild cognitive impairment, Alzheimer.
Eight registered trials have looked at this, and not one of them has reported a result.
Species by species
| Species | How far it has got | Trials | With a result | Randomised | Commonly taken for it |
|---|---|---|---|---|---|
| Lion's mane Hericium erinaceus | Repeated trials | 5 | 0 | 3 | yes |
| Reishi Ganoderma lucidum | Repeated trials | 1 | 0 | 2 | — |
| Cordyceps Cordyceps militaris | A first trial | 1 | 0 | 1 | — |
| Maitake Grifola frondosa | A first trial | 0 | 0 | 1 | — |
| Tremella Tremella fuciformis | Being tested now | 1 | 0 | 0 | yes |
| Poria Wolfiporia extensa | Laboratory work | 0 | 0 | 0 | — |
The trials themselves
Every registered study that names one of these species and a condition the register files under this heading.
| Register | Study | Condition | People | Status | Result posted | Dose in the protocol |
|---|---|---|---|---|---|---|
| NCT06870136 | Study Evaluating the Quality and Effects of Lion's Mane Product on Cognitive Health | Cognitive Decline | 150 | Recruiting | — | — |
| NCT01718548 | The Effects of Cordyceps Sinensis and Lingzhi on Cardiovascular Fitness and Cognitive Function | Physical Fitness, Executive Function | 100 | Unknown | — | — |
| NCT01718548 | The Effects of Cordyceps Sinensis and Lingzhi on Cardiovascular Fitness and Cognitive Function | Physical Fitness, Executive Function | 100 | Unknown | — | — |
| NCT07405957 | Effects of Two Different Lion's Mane Extracts (Lions Mane Fruiting Body & Lions Mane Fruiting Body With Mycell | Healthy Adult Females, Healthy Adult Male | 87 | Completed | — | — |
| NCT07405632 | The Impact of Supplementation With Hericium Erinaceus (Lion's Mane) Extract on Cognitive Functioning | Attention, Memory | 85 | Completed | — | 20,000 mg, 1ml per day |
| NCT02377024 | Effects of Tremella Fuciformis on Improvement in Cognitive-Bio-Markers of Cognitive Functions | Healthy Adults With Subjective Memory Complaints | 75 | Completed | — | 600mg, 1200mg |
| NCT04065061 | Erinacine A-enriched Hericium Erinaceus Mycelia for Improvement of Recognition, Vision, and Functional MRI Alt | Supplement, Cognition Disorders in Old Age | 68 | Completed | — | — |
| NCT04939961 | Effects of Hericium Erinaceus on Microbiota and Cognition | Cognitive Decline, Mild | 40 | Completed | — | 6 capsule |
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