Updated
Inflammation
Cordyceps, button mushroom, shiitake and two others have been tried in people for this. The register's own words for this are inflammation, C-reactive protein, oxidative stress.
Seven registered trials have looked at this, and 1 of them reported.
Species by species
| Species | How far it has got | Trials | With a result | Randomised | Commonly taken for it |
|---|---|---|---|---|---|
| Cordyceps Cordyceps militaris | A first trial | 2 | 0 | 1 | — |
| Button mushroom Agaricus bisporus | A first trial | 1 | 0 | 1 | — |
| Shiitake Lentinula edodes | A first trial | 1 | 1 | 0 | — |
| Reishi Ganoderma lucidum | Being tested now | 2 | 0 | 0 | — |
| Turkey tail Trametes versicolor | Being tested now | 1 | 0 | 0 | — |
| Artist's conk Ganoderma applanatum | Laboratory work | 0 | 0 | 0 | yes |
| Birch polypore Fomitopsis betulina | Laboratory work | 0 | 0 | 0 | yes |
| Chaga Inonotus obliquus | Laboratory work | 0 | 0 | 0 | yes |
Commonly taken for inflammation, with the work still in the laboratory rather than in people: Artist's conk, Birch polypore, Chaga.
The trials themselves
Every registered study that names one of these species and a condition the register files under this heading.
| Register | Study | Condition | People | Status | Result posted | Dose in the protocol |
|---|---|---|---|---|---|---|
| NCT04186780 | Effects of Lentinula Edodes Bars on Dyslipidemia and Oxidative Stress in Cholesterol Individuals: Randomized S | Dyslipidemias | 68 | Completed | yes | — |
| NCT07316400 | PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers | Oxidative Stress, Inflammation | 200 | Completed | — | 250 mg, 180 mg |
| NCT07316400 | PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers | Oxidative Stress, Inflammation | 200 | Completed | — | 250 mg, 180 mg |
| NCT07564947 | Impact of Ganoderma Lucidum on NRF2 Levels and Antioxidant Status in Metabolic Asscociated Fatty Liver Disease | MAFLD, Fatty Liver | 40 | Enrolling by invitation | — | — |
| NCT07664345 | Effect of Cordyceps Supplementation Timing on Physiological Responses and Aerobic Adaptation in Athletes | Exercise Recovery, Exercise-induced Muscle Damage | 30 | Completed | — | 200 mg, 2,000 mg |
| NCT04913064 | Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer | Breast Carcinoma | 26 | Recruiting | — | — |
| NCT07726979 | The Combined Effects of Cordyceps and Fartlek Training on Muscle Recovery and Bone Health in Soccer Players | Muscle Damage, Athletic Performance | 22 | Completed | — | 500 mg |
Memory and focusMood and anxietySleepFatigue and energyImmune functionCancer, supportive and adjuvantBlood sugarCholesterol and lipidsGut and microbiomeExercise performanceLiverSkinLungs and breathingKidneyNerve repairAllergyMouth and gumsLibido and fertilityBlood and clottingViral infectionBacterial infectionWound healingFluid retentionNutrition