Updated
Mesima
A hard bracket on mulberry, taken in Korea and Japan as an immune preparation. One Korean product carries its own trial record.
Repeated trials
Where it stands: 1 registered trial in people, which has not reported; 2 randomised trials published since 2022.
What it is taken for
One tile per use. The line under each is how far the evidence for that use actually got, counted rather than argued.
What it has been tried for, and how far that has got
One row per use. The label is counted rather than argued — it is set by how many randomised trials and posted results exist for that use, and nothing else. How that is worked out.
| Use | How far it has got | Trials | With a result | Randomised, published | Reviews | Commonly taken for it |
|---|---|---|---|---|---|---|
| Immune function | Repeated trials | 0 | 0 | 2 | 0 | yes |
| Fatigue and energy | Being tested now | 1 | 0 | 0 | 0 | — |
| Cancer, supportive and adjuvant | Laboratory work | 0 | 0 | 0 | 0 | yes |
| Liver | Laboratory work | 0 | 0 | 0 | 0 | yes |
Commonly taken for cancer, supportive and adjuvant, liver. The work there is still laboratory and animal work — often a great deal of it — and the step into a trial in people has not been taken yet.
The doses the protocols actually specify
Taken verbatim from the intervention description each trial filed. These are not recommendations and they are not comparable to each other: some are a whole-mushroom powder, some a purified fraction.
| Dose as filed | Study | Condition | People |
|---|---|---|---|
4 g | Sanghuangporus Sanghuang Supplementation to Improve Anti-Fatigue Performance in | Nutritional Supplementation, Physical Performanc | 58 |
2 capsule | Sanghuangporus Sanghuang Supplementation to Improve Anti-Fatigue Performance in | Nutritional Supplementation, Physical Performanc | 58 |
4 capsule | Sanghuangporus Sanghuang Supplementation to Improve Anti-Fatigue Performance in | Nutritional Supplementation, Physical Performanc | 58 |
Every registered study that names it
From ClinicalTrials.gov, filtered to studies that name Phellinus linteus or a synonym in the title, summary or intervention. Studies that have posted results come first.
| Register | Study | Condition | People | Status | Result posted | Dose in the protocol |
|---|---|---|---|---|---|---|
| NCT06902662 | Sanghuangporus Sanghuang Supplementation to Improve Anti-Fatigue Performance in Healthy Adults | Nutritional Supplementation, Physical Performance | 58 | Completed | — | 4 g, 2 capsule |
The compounds the research names
Formula and mass from PubChem. Naming a compound is not a claim that it does anything in a person.
C13H10O5
C18H32O16
In the kitchen
Hard, woody and bitter.
Not eaten. Simmered as a decoction or taken as a standardised extract in Korea and Japan.
Where it has been recorded, and when it fruits
159 verified occurrence records with coordinates, from GBIF. This is where people have recorded it, which follows where recorders live as much as where the fungus grows — read the shape, not the ranking.
| Brazil | 40 | |
| Costa Rica | 21 | |
| Mexico | 16 | |
| Australia | 11 | |
| UZ | 11 | |
| Argentina | 7 | |
| NI | 7 | |
| Russia | 5 | |
| TM | 4 | |
| TZ | 4 | |
| GF | 3 | |
| India | 3 |
Most records fall in Jan. Northern-hemisphere recorders dominate the dataset, so a southern population would not show here.
iNaturalist separately holds 3 research-grade observations of it.
What has been reported going wrong
No voluntary adverse-event report to the US Food and Drug Administration names a product by this name. That is an absence of reports, not a demonstration of safety: these are the products least likely to be reported on, because nobody is required to.
The newest randomised trials and reviews
Indexed in Europe PMC. Titles and journals only — follow the link to read the paper where the publisher allows it.
| Year | Study | Journal | Kind | Citations |
|---|---|---|---|---|
| 2023 | Polysaccharides from Phellinus linteus: A systematic review of their extractions, purifications, structures and function | Int J Biol Macromol | Review or meta-analysis | 25 |
| 2022 | Efficacy of Phellinus linteus extract on immunity enhancement: A CONSORT-randomized, double-blind, placebo-controlled pi open access | Medicine (Baltimore) | Randomised trial | 4 |
| 2022 | Effects of Phellinus linteus extract on immunity improvement: A CONSORT-randomized, double-blinded, placebo-controlled t open access | Medicine (Baltimore) | Randomised trial | 3 |